Vulval superficial myofibroblastoma with lymphocytic and eosinophilic infiltrate

BMJ Case Rep. 2023 Nov 30;16(11):e248800. doi: 10.1136/bcr-2022-248800.


We present the case of a vulval superficial myofibroblastoma with a lymphocytic and eosinophilic rim in a woman in her late 20s. The tumour presented in pregnancy as a cystic lesion with pain and increasing size. While the histopathology of superficial myofibroblastomas has been well defined in the literature, to our knowledge, there has been no documentation of the presence of an inflammatory infiltrate of lymphocytes and eosinophils surrounding and within the tumour. This may potentially act as a diagnostic or prognostic reference.

Keywords: Obstetrics and gynaecology; Pathology.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia* / pathology
  • Eosinophils / pathology
  • Female
  • Humans
  • Lymphocytes / pathology
  • Neoplasms, Muscle Tissue* / diagnosis
  • Neoplasms, Muscle Tissue* / pathology
  • Neoplasms, Muscle Tissue* / surgery
  • Vulvar Neoplasms* / diagnosis
  • Vulvar Neoplasms* / pathology
  • Vulvar Neoplasms* / surgery