An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications

Drug Deliv. 2023 Dec;30(1):2241667. doi: 10.1080/10717544.2023.2241667. Epub 2023 Dec 1.

Abstract

Nanotechnology has made significant progress in various fields, including medicine, in recent times. The application of nanotechnology in drug delivery has sparked a lot of research interest, especially due to its potential to revolutionize the field. Researchers have been working on developing nanomaterials with distinctive characteristics that can be utilized in the improvement of drug delivery systems (DDS) for the local, targeted, and sustained release of drugs. This approach has shown great potential in managing diseases more effectively with reduced toxicity. In the medical field of orthopedics, the use of nanotechnology is also being explored, and there is extensive research being conducted to determine its potential benefits in treatment, diagnostics, and research. Specifically, nanophase drug delivery is a promising technique that has demonstrated the capability of delivering medications on a nanoscale for various orthopedic applications. In this article, we will explore current advancements in the area of nanostructured DDS for orthopedic use.

Keywords: Nanotechnology; bone; drug delivery system; orthopedic; tumor.

MeSH terms

  • Drug Delivery Systems
  • Nanostructures*
  • Nanotechnology / methods
  • Orthopedic Procedures* / methods
  • Orthopedics* / methods
  • Pharmaceutical Preparations

Substances

  • Pharmaceutical Preparations