Biostimulation of wound healing by lasers: experimental approaches in animal models and in fibroblast cultures

J Dermatol Surg Oncol. 1987 Feb;13(2):127-33. doi: 10.1111/j.1524-4725.1987.tb00510.x.


Recent evidence suggests that low-energy lasers, such as an He-Ne laser, might stimulate wound healing. In this review we are summarizing our recent observations indicating that low-energy lasers enhance collagen gene expression both in skin fibroblast cultures in vitro, as well as in animal models of wound healing in vivo.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Division / radiation effects
  • Cells, Cultured
  • Collagen / biosynthesis
  • Fibroblasts / radiation effects
  • Humans
  • Lasers*
  • Mice
  • Mice, Hairless
  • Protein Biosynthesis
  • Tensile Strength / radiation effects
  • Wound Healing / radiation effects*


  • Collagen