MicroRNA and long non-coding RNA analysis in IgM-monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis

Karan Chohan; Jonas Paludo; Surendra Dasari; Patrizia Mondello; Joseph P Novak; Jithma P Abeykoon; Kerstin Wenzl; Zhi-Zhang Yang; Shahrzad Jalali; Jordan E Krull; Esteban Braggio; Michelle K Manske; Aneel Paulus; Craig B Reeder; Sikander Ailawadhi; Asher Chanan-Khan; Prashant Kapoor; Robert A Kyle; Morie A Gertz; Anne J Novak; Stephen M Ansell

doi:10.3324/haematol.2023.283927

MicroRNA and long non-coding RNA analysis in IgM-monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis

Haematologica. 2024 May 1;109(5):1570-1575. doi: 10.3324/haematol.2023.283927.

Authors

Karan Chohan¹, Jonas Paludo², Surendra Dasari³, Patrizia Mondello², Joseph P Novak², Jithma P Abeykoon², Kerstin Wenzl², Zhi-Zhang Yang², Shahrzad Jalali², Jordan E Krull², Esteban Braggio⁴, Michelle K Manske², Aneel Paulus⁵, Craig B Reeder⁴, Sikander Ailawadhi⁵, Asher Chanan-Khan⁵, Prashant Kapoor², Robert A Kyle², Morie A Gertz², Anne J Novak², Stephen M Ansell⁶

Affiliations

¹ Department of Medicine, Mayo Clinic, Rochester, MN.
² Division of Hematology, Mayo Clinic, Rochester, MN.
³ Department of Health Sciences Research, Mayo Clinic, Rochester, MN.
⁴ Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ.
⁵ Division of Hematology and Oncology, Mayo Clinic, Jacksonville, FL.
⁶ Division of Hematology, Mayo Clinic, Rochester, MN. ansell.stephen@mayo.edu.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Carcinogenesis / genetics
Epigenesis, Genetic*
Humans
Immunoglobulin M* / genetics
MicroRNAs* / genetics
Paraproteinemias / genetics
RNA, Long Noncoding* / genetics

Substances

MicroRNAs
RNA, Long Noncoding
Immunoglobulin M

Grants and funding

Funding: This study was supported by research funding from the BINK Foundation, and International Waldenström Macroglobulinemia Foundation (IWMF) to SMA and the Mayo Clinic.