Facial Cutaneous Rosai-Dorfman Disease: Dermoscopic Findings with Successful Surgical Treatment

Keunyoung Hur; Ji Yeon Hong; Kyu Han Kim; Jihui Jeon; Cheol Lee; Yoonjin Kwak; Tae Min Kim; Je-Ho Mun

doi:10.5021/ad.22.071

Facial Cutaneous Rosai-Dorfman Disease: Dermoscopic Findings with Successful Surgical Treatment

Ann Dermatol. 2023 Nov;35(Suppl 2):S287-S291. doi: 10.5021/ad.22.071.

Authors

Keunyoung Hur¹, Ji Yeon Hong¹, Kyu Han Kim¹, Jihui Jeon², Cheol Lee³, Yoonjin Kwak³, Tae Min Kim⁴, Je-Ho Mun⁵

Affiliations

¹ Department of Dermatology, Seoul National University Hospital, Seoul, Korea.
² Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Korea.
³ Department of Pathology, Seoul National University Hospital, Seoul, Korea.
⁴ Department of Internal Medicine, Seoul National University Cancer Research Institute, Seoul National University Hospital, Seoul, Korea.
⁵ Department of Dermatology, Seoul National University Hospital, Seoul, Korea. jehomun@gmail.com.

Abstract

Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis characterized by an accumulation of activated histiocytes within the affected tissues. It is a heterogeneous disease that includes the classical (nodal) and extra-nodal variants. The cutaneous form of the disease without the characteristic lymphadenopathy is rare and is often misdiagnosed as other dermatologic diseases. Misdiagnosis as lymphoproliferative and infectious diseases such as lymphoma and tuberculosis have been reported in the literature. Herein, we report a case of facial cutaneous RDD with successful surgical treatment. In addition, we provide dermoscopic findings and literature review as dermoscopy can be a useful adjuvant tool in the diagnosis of cutaneous RDD.

Keywords: Dermoscopy; Histiocytes; Histiocytosis; Rosai-Dorfman disease; Surgery; Treatment.

Publication types

Case Reports