Plant histone variants at the nexus of chromatin readouts, stress and development

Biochim Biophys Acta Gen Subj. 2024 Feb;1868(2):130539. doi: 10.1016/j.bbagen.2023.130539. Epub 2023 Dec 10.

Abstract

Histones are crucial proteins that are involved in packaging the DNA as condensed chromatin inside the eukaryotic cell nucleus. Rather than being static packaging units, these molecules undergo drastic variations spatially and temporally to facilitate accessibility of DNA to replication, transcription as well as wide range of gene regulatory machineries. In addition, incorporation of paralogous variants of canonical histones in the chromatin is ascribed to specific functions. Given the peculiar requirement of plants to rapidly modulate gene expression levels on account of their sessile nature, histones and their variants serve as additional layers of gene regulation. This review summarizes the mechanisms and implications of distribution, modifications and differential incorporation of histones and their variants across plant genomes, and outlines emerging themes.

Keywords: Gene regulation; Histone modifications; Histone variants; Plant epigenetics.

Publication types

  • Review

MeSH terms

  • Chromatin* / genetics
  • DNA
  • Gene Expression Regulation
  • Histones* / genetics
  • Histones* / metabolism
  • Plants / genetics
  • Plants / metabolism

Substances

  • Chromatin
  • Histones
  • DNA