Sharp recanalization of CBD occlusion in patient with second orthotropic liver transplant with cocoon syndrome

Radiol Case Rep. 2023 Nov 28;19(2):691-694. doi: 10.1016/j.radcr.2023.11.011. eCollection 2024 Feb.


Biliary complications after orthotopic liver transplant (OLT) remain one of the primary causes of morbidity and mortality in liver transplant recipients with an approximate incidence between 5% and 32%. Given the limited supply of hepatic grafts, one of the most feared outcomes as a result of biliary complications is acute and or chronic graft failure. Biliary complications include leaks, biliary stasis, and stone formation, sphincter of Oddi dysfunction, recurrence of biliary disease (primary sclerosing cholangitis and primary biliary cirrhosis), and biliary strictures/obstruction. Overwhelmingly, the most common complication in hepatic transplantation is biliary stricture formation accounting for more than 50%. Currently, the mainstay of therapy as it pertains to biliary strictures/obstruction includes endoscopic retrograde cholangiography-guided therapy, percutaneous transhepatic cholangiography-guided therapy, or surgical revision/retransplantation. We present a case of biliary obstruction in a patient with a second liver transplant complicated by Cocoon Syndrome managed via sharp recanalization of CBD occlusion and placement of an endoscopic biliary Viabil stent.

Keywords: Cocoon syndrome; Liver transplant; Sharp recanalization.

Publication types

  • Case Reports