A rare case report of muscular metastasis of prostate cancer

Mohsen Ayati; Mohsen Shiraghaee; Erfan Amini; Nasser Rakhshani; Laleh Sharifi

doi:10.1016/j.eucr.2023.102619

A rare case report of muscular metastasis of prostate cancer

Urol Case Rep. 2023 Nov 27:51:102619. doi: 10.1016/j.eucr.2023.102619. eCollection 2023 Nov.

Authors

Mohsen Ayati¹, Mohsen Shiraghaee¹, Erfan Amini¹, Nasser Rakhshani², Laleh Sharifi¹

Affiliations

¹ Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
² Department of Pathology, Gastrointestinal and Liver Diseases Research Centre, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

Abstract

Skeletal muscle metastasis of prostate cancer is a very rare phenomenon that has only been described in limited case reports. In this study, we present a case of neuroendocrine prostate cancer with muscle metastasis, a histological subtype associated with a grim prognosis. This case illustrates the potential efficacy of urgent surgical resection of the metastatic muscle mass, followed by adjuvant radiation therapy, as a suitable management strategy for this condition. However, a comprehensive understanding of the biological characteristics of neuroendocrine prostate cancer is imperative in our fight against this lethal form of the disease and in the prevention of metastatic spread.

Keywords: Metastasis; Neuroendocrine differentiation; Prostate cancer; Skeletal muscle.

Publication types

Case Reports