Calciphylaxis in a Patient With Lupus Nephritis and Acute Kidney Injury: A Rare Case Report and Literature Review

J Investig Med High Impact Case Rep. 2023 Jan-Dec:11:23247096231215705. doi: 10.1177/23247096231215705.

Abstract

Calciphylaxis is a rare and severe disease characterized by calcification, fibrosis, and thrombosis of small blood vessels. Although it primarily affects patients with end-stage renal disease (ESRD) on dialysis, limited cases have been reported of calciphylaxis in patients with acute kidney injury (AKI) and lupus. This case report describes the occurrence of calciphylaxis in a 35-year-old female recently diagnosed with lupus nephritis class IV and AKI requiring dialysis.

Keywords: acute kidney injury; calciphylaxis; lupus nephritis; systemic lupus erythematosus (SLE).

Publication types

  • Review
  • Case Reports

MeSH terms

  • Acute Kidney Injury* / etiology
  • Adult
  • Calciphylaxis* / diagnosis
  • Calciphylaxis* / etiology
  • Female
  • Humans
  • Kidney Failure, Chronic* / complications
  • Kidney Failure, Chronic* / therapy
  • Lupus Nephritis* / complications
  • Lupus Nephritis* / diagnosis
  • Renal Dialysis / adverse effects