Gaschromatographic determination of polycyclic aromatic hydrocarbons, aza-arenes, aromatic amines in the particle and vapor phase of mainstream and sidestream smoke of cigarettes

Toxicol Lett. 1987 Jan;35(1):117-24. doi: 10.1016/0378-4274(87)90095-6.


The present arrangement collects particles and semivolatiles of main- and sidestream smoke and allows a recovery of the trapped substances nearly quantitatively and without impurities. The fractionation procedure allows to separate various groups of carcinogens such as PAH, aza-arenes and aromatic amines for analytical and biological studies. Sidestream smoke contains ten times more polycyclic aromatic hydrocarbons (PAH) compared with mainstream smoke. This holds also true for aza-arenes and amines. PAH of the gaseous phases include only 1% of the particle-bound PAH.

MeSH terms

  • Aerosols
  • Amines / analysis*
  • Aza Compounds / analysis*
  • Chromatography, Gas
  • Gases / analysis
  • Heterocyclic Compounds / analysis*
  • Plants, Toxic*
  • Polycyclic Compounds / analysis*
  • Smoke / analysis*
  • Tobacco / analysis*
  • Tobacco Smoke Pollution / analysis*


  • Aerosols
  • Amines
  • Aza Compounds
  • Gases
  • Heterocyclic Compounds
  • Polycyclic Compounds
  • Smoke
  • Tobacco Smoke Pollution