Hydroxy-phenanthrenes in the urine of non-smokers and smokers

Toxicol Lett. 1987 Jan;35(1):67-71. doi: 10.1016/0378-4274(87)90087-7.


Urinary hydroxy-phenanthrene (HO-PHE) excretion in non-smokers exposed to environmental tobacco smoke (ETS) is not increased. There is no significant difference in HO-PHE excretion between smokers (S) and non-smokers (NS), though excretion seems to be slightly elevated in smokers. A diet rich in polycyclic aromatic hydrocarbons leads to a rise in urinary HO-PHE excretion as compared to a diet low in polycyclic aromatic hydrocarbons (PAH), coming close to significance. HO-PHE excretion is not correlated with the mutagenic activity in urine.

MeSH terms

  • Diet
  • Humans
  • Phenanthrenes / urine*
  • Smoking*
  • Tobacco Smoke Pollution / analysis*


  • Phenanthrenes
  • Tobacco Smoke Pollution