B antigen acquired by normal A1 red cells exposed to a patient's serum

Transfusion. 1987 Jan-Feb;27(1):41-4. doi: 10.1046/j.1537-2995.1987.27187121471.x.


The authors report a patient with the acquired B antigen whose serum contained a factor capable of inducing the acquired B phenotype on normal A1 red cells in vitro. The patient's red cells were not, however, agglutinated by a monoclonal anti-B. These findings and the abolition of the acquired B antigen by treatment of the patient's red cells with acetic anhydride support the deacetylation theory of the genesis of the acquired B antigen.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • ABO Blood-Group System / immunology*
  • Acetylation
  • Aged
  • Antibodies, Monoclonal
  • Carbohydrate Sequence
  • Erythrocytes / immunology*
  • Hemagglutination
  • Humans
  • Male


  • ABO Blood-Group System
  • Antibodies, Monoclonal