An anthropometric study of 38 individuals with Prader-Labhart-Willi syndrome

Am J Med Genet. 1987 Feb;26(2):445-55. doi: 10.1002/ajmg.1320260224.


Weight, height, sitting height, and 24 other anthropometric variables (5 body circumferences, skinfolds at 7 sites, 4 head dimensions, and 8 hand and foot measurements) were obtained on 38 Prader-Labhart-Willi syndrome (PLWS) individuals (21 with apparent chromosome 15 deletions and 17 nondeletion cases) with an age range of 2 weeks to 38 1/2 years. More than half of these individuals were measured on more than one occasion. The measurements confirmed the presence of short stature, small hands and feet, obesity, and narrow bi-frontal diameter in PLWS. No differences were found for the anthropometric measurements between the 2 chromosome subgroups. Inverse correlations were produced with linear measurements (eg, height, hand and foot lengths) and age, which indicated a deceleration of linear growth relative to normal individuals with increasing age.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Anthropometry
  • Body Composition
  • Child
  • Child, Preschool
  • Chromosome Deletion
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Karyotyping
  • Male
  • Prader-Willi Syndrome / genetics
  • Prader-Willi Syndrome / pathology*