[Infectious Gastric Diseases Other than Helicobacter]

Korean J Gastroenterol. 2023 Dec 25;82(6):269-281. doi: 10.4166/kjg.2023.139.
[Article in Korean]

Abstract

In addition to Helicobacter pylori, the acute bacterial causes of infectious gastritis, include phlegmonous gastritis, gastric tuberculosis, and gastric syphilis. Bacterial gastritis often improves with appropriate broad-spectrum antibiotics, emphasizing the need for prompt diagnosis and treatment based on the clinical and endoscopic findings. Among viral gastritis, cytomegalovirus gastritis, primarily occurring in immunocompromised patients, necessitates antiviral intervention, while immunocompetent individuals typically achieve amelioration by administering proton pump inhibitors. In contrast, most gastric infections caused by the Epstein-Barr virus (EBV) are asymptomatic, but an EBV infection is a cause of stomach cancer. EBV-associated gastric cancer exhibits distinct clinical, pathological, genetic, and post-genetic mutation features, making it clinically significant. The colonization of Candida albicans in the stomach is uncommon, and typical antifungal treatment is unnecessary. Candida infections in gastric ulcers can be treated with anti-ulcer treatment alone. Lastly, anisakidosis in the stomach, which occurs when consuming raw seafood, can manifest in various clinical presentations and is typically treated through endoscopic removal of the nematode. This article aims to contribute to the rapid diagnosis and treatment of rare stomach infections beyond Helicobacter pylori in real clinical situations.

Keywords: Cytomegalovirus gastritis; Ebstein-Barr virus gastritis; Gastric candidiasis; Gastric syphilis; Phlegmonous gastritis.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Epstein-Barr Virus Infections* / complications
  • Gastritis* / diagnosis
  • Gastritis* / drug therapy
  • Helicobacter Infections* / complications
  • Helicobacter Infections* / diagnosis
  • Helicobacter Infections* / drug therapy
  • Helicobacter pylori*
  • Helicobacter*
  • Herpesvirus 4, Human / genetics
  • Humans
  • Stomach Neoplasms* / pathology