Neutralizing Immunity Against Antigenically Advanced Omicron BA.5 in Children After SARS-CoV-2 Infection

J Pediatric Infect Dis Soc. 2024 Jan 29;13(1):100-104. doi: 10.1093/jpids/piad109.


We assessed serum neutralization of Omicron BA.5 in children following SARS-CoV-2 infection during the Delta or Omicron BA.1/BA.2 variant period. Convalescent BA.5 titers were higher following infections during the Omicron BA.1/BA.2 vs Delta variant period, and in vaccinated vs unvaccinated children. Titers against BA.5 did not differ by age group.

Keywords: Omicron; SARS-CoV-2 infection; cross-neutralization; neutralizing antibodies.

MeSH terms

  • Antibodies, Viral
  • COVID-19*
  • Child
  • Humans
  • SARS-CoV-2


  • Antibodies, Viral

Supplementary concepts

  • SARS-CoV-2 variants