A single-institution retrospective evaluation of noninvasive localization for non-palpable breast microcalcification

Asian J Surg. 2024 Apr;47(4):1776-1780. doi: 10.1016/j.asjsur.2023.12.086. Epub 2023 Dec 23.


Technique: From January 1, 2018, to December 31, 2021, we localized the breast microcalcification of 40 patients before the surgical excision. We measured the distance between the nipple and the center of the calcification on the CC view and the ML view, respectively. The operation proceeded around the intersection between two lines, slightly larger than the diameter of the microcalcification. We also analyze the pathological findings.

Results: All 40 patients successfully detected calcification by mammograms preoperatively using the method mentioned above. 38 patients have the microcalcification removal within the one-time operation, while the other two underwent an extended lumpectomy. 20 of 40 calcifications (50 %) were malignant and 12(30 %) were precancerous lesions. In the group of women older than 45 years old, the percentages of malignant and atypical hyperplasias are 56.25 % (18/32) and 31.25 % (10/32) respectively.

Conclusion: Our non-invasive method of preoperative localization is safe and cost-effective. Furthermore, initial observations suggest that there may be a link between age and malignant microcalcification.

Keywords: Breast cancer; Localization; Mammography; Non-invasive; Non-palpable breast microcalcification.

MeSH terms

  • Breast Diseases* / diagnostic imaging
  • Breast Diseases* / pathology
  • Breast Diseases* / surgery
  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / surgery
  • Calcinosis* / diagnostic imaging
  • Calcinosis* / pathology
  • Calcinosis* / surgery
  • Female
  • Humans
  • Mammography
  • Mastectomy, Segmental
  • Middle Aged
  • Retrospective Studies