Association of previously irradiated stable brain metastases with outcomes of atezolizumab-treated non-small cell lung cancer: A pooled analysis of individual patient data from three randomized trials

Tiantian Guo; Yue Zhou; Fei Liang; Zezhou Wang; Vincent Bourbonne; Lukas Käsmann; Nora Sundahl; Abraham Jing-Ching Wu; Jianjiao Ni; Zhengfei Zhu

doi:10.1002/cac2.12512

Association of previously irradiated stable brain metastases with outcomes of atezolizumab-treated non-small cell lung cancer: A pooled analysis of individual patient data from three randomized trials

Cancer Commun (Lond). 2024 Feb;44(2):278-281. doi: 10.1002/cac2.12512. Epub 2023 Dec 25.

Authors

Tiantian Guo^{1

2

3

4}, Yue Zhou^{1

2

3

4}, Fei Liang⁵, Zezhou Wang^{2

6}, Vincent Bourbonne⁷, Lukas Käsmann⁸, Nora Sundahl⁹, Abraham Jing-Ching Wu¹⁰, Jianjiao Ni^{1

2

3

4}, Zhengfei Zhu^{1

2

3

4

11}

Affiliations

¹ Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
² Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, P. R. China.
³ Shanghai Clinical Research Center for Radiation Oncology, Shanghai, P. R. China.
⁴ Shanghai Key Laboratory of Radiation Oncology, Shanghai, P. R. China.
⁵ Department of Biostatistics, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
⁶ Department of Cancer Prevention, Fudan University Shanghai Cancer Center, Shanghai, P. R. China.
⁷ Radiation Oncology Department, University Hospital, Brest, France.
⁸ Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
⁹ Department of Radiation Oncology, AZ Groeninge, Kortrijk, Belgium.
¹⁰ Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
¹¹ Institute of Thoracic Oncology, Fudan University, Shanghai, P. R. China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Monoclonal, Humanized*
Brain Neoplasms* / drug therapy
Brain Neoplasms* / radiotherapy
Carcinoma, Non-Small-Cell Lung* / drug therapy
Carcinoma, Non-Small-Cell Lung* / pathology
Carcinoma, Non-Small-Cell Lung* / radiotherapy
Humans
Lung Neoplasms* / drug therapy
Lung Neoplasms* / pathology
Lung Neoplasms* / radiotherapy
Randomized Controlled Trials as Topic

Substances

atezolizumab
Antibodies, Monoclonal, Humanized

Grants and funding

P30 CA008748/CA/NCI NIH HHS/United States