Abstract
Dietary administration of the growth promoter, clenbuterol, ameliorated denervation-induced atrophy in rat soleus muscles. In acutely denervated muscles the drug inhibited the appearance of atrophy, and in chronically denervated muscles the atrophy was almost fully reversed. Responses in slow twitch oxidative fibres were particularly marked.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Clenbuterol / pharmacology*
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Ethanolamines / pharmacology*
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Glycolysis
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Male
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Muscle Contraction
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Muscle Denervation*
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Muscle Development*
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Muscle Proteins / metabolism
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Muscles / drug effects
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Muscular Atrophy / drug therapy*
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Muscular Atrophy / pathology
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Rats
Substances
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Ethanolamines
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Muscle Proteins
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Clenbuterol