Optical Coherence Tomography Feature of Retinoschisis in CRB1-Associated Maculopathy

Julia-Sophia Bellingrath; Johannes Birtel; Imran H Yusuf; Robert E MacLaren; Peter Charbel Issa

doi:10.1001/jamaophthalmol.2023.5886

Optical Coherence Tomography Feature of Retinoschisis in CRB1-Associated Maculopathy

JAMA Ophthalmol. 2024 Feb 1;142(2):158-161. doi: 10.1001/jamaophthalmol.2023.5886.

Authors

Julia-Sophia Bellingrath^{1

2}, Johannes Birtel^{1

2

3}, Imran H Yusuf^{1

2}, Robert E MacLaren^{1

2}, Peter Charbel Issa^{1

2}

Affiliations

¹ Oxford Eye Hospital, Oxford University Hospitals National Health Service Foundation Trust, John Radcliffe Hospital, Oxford, United Kingdom.
² Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
³ Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

PMID: 38153728
DOI: 10.1001/jamaophthalmol.2023.5886

No abstract available

Plain language summary

This case report describes 2 individuals with hyperreflective columns in the outer nuclear layer observed on optical coherence tomography and possible implications for CRB1-associated maculopathy.

MeSH terms

Eye Proteins / genetics
Fovea Centralis
Humans
Macular Degeneration*
Membrane Proteins
Nerve Tissue Proteins
Retinal Diseases*
Retinoschisis* / diagnostic imaging
Retinoschisis* / genetics
Tomography, Optical Coherence / methods

Substances

CRB1 protein, human
Eye Proteins
Membrane Proteins
Nerve Tissue Proteins