In vitro activity of CI-934 and other antimicrobial agents against gram-positive and gram-negative bacteria

Clin Ther. 1986;9(1):106-18.

Abstract

The activity of CI-934, a new carboxy-quinolone antibiotic, against gram-positive cocci and bacilli and gram-negative bacilli was compared with that of reference antibiotics. CI-934 demonstrated excellent activity against gram-positive organisms, including Corynebacterium sp. In addition, although the activity of CI-934 against gram-negative bacilli was less than that reported for similar agents, it was comparable to that of aminoglycosidic aminocyclitol antibiotics.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Fluoroquinolones*
  • Gram-Negative Bacteria / drug effects*
  • Microbial Sensitivity Tests
  • Quinolines / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Fluoroquinolones
  • Quinolines
  • CI 934