In noncardiac thoracic surgery, low-dose colchicine did not reduce AF or myocardial injury after noncardiac surgery at 14 d

Ann Intern Med. 2024 Jan;177(1):JC3. doi: 10.7326/J23-0103. Epub 2024 Jan 2.

Abstract

Conen D, Ke Wang M, Popova E, et al; COP-AF Investigators. Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an international randomised trial. Lancet. 2023;402:1627-1635. 37640035.

Publication types

  • Comment

MeSH terms

  • Atrial Fibrillation* / drug therapy
  • Atrial Fibrillation* / etiology
  • Atrial Fibrillation* / prevention & control
  • Colchicine / adverse effects
  • Humans
  • Postoperative Complications / prevention & control
  • Thoracic Surgery*

Substances

  • Colchicine