Subclinical hypothyroidism in the infertile female population: a guideline

Fertil Steril. 2024 May;121(5):765-782. doi: 10.1016/j.fertnstert.2023.12.038. Epub 2023 Dec 30.

Abstract

There is controversy regarding whether to treat subtle abnormalities of thyroid function in infertile female patients. This guideline document reviews the risks and benefits of treating subclinical hypothyroidism in female patients with a history of infertility and miscarriage, as well as obstetric and neonatal outcomes in this population.

Keywords: Thyroid-stimulating hormone; levothyroxine; pregnancy; pregnancy loss; subclinical hypothyroidism.

Publication types

  • Practice Guideline

MeSH terms

  • Asymptomatic Diseases*
  • Female
  • Humans
  • Hypothyroidism* / complications
  • Hypothyroidism* / diagnosis
  • Hypothyroidism* / epidemiology
  • Hypothyroidism* / therapy
  • Infertility, Female* / diagnosis
  • Infertility, Female* / epidemiology
  • Infertility, Female* / physiopathology
  • Infertility, Female* / therapy
  • Pregnancy
  • Risk Factors
  • Treatment Outcome