Nodular and diffuse spindle cell infiltration in keloidal scleroderma: a case report

Yiting Li; Yibin Zeng; Zile Chen; Shu Nie; Zhouwei Wu

doi:10.3389/fmed.2023.1291941

Nodular and diffuse spindle cell infiltration in keloidal scleroderma: a case report

Front Med (Lausanne). 2023 Dec 18:10:1291941. doi: 10.3389/fmed.2023.1291941. eCollection 2023.

Authors

Yiting Li^#¹, Yibin Zeng^#², Zile Chen¹, Shu Nie¹, Zhouwei Wu¹

Affiliations

¹ Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
² Department of Dermatology, Minhang Hospital, Fudan University, Shanghai, China.

^# Contributed equally.

Abstract

Keloidal scleroderma is a variant of scleroderma that presents as firm keloidal nodules or plaques. Due to the similarity in morphology and pathology, it is often distinguished from a hypertrophic scar or keloid. We report a case of keloidal scleroderma with rare nodular and diffuse spindle cell infiltration in histopathology. Recognition of this unusual histopathological feature may help clinicians improve their knowledge and avoid misdiagnosis.

Keywords: CD34; case report; keloidal scleroderma; nephrogenic systemic fibrosis; spindle cell infiltration.

Publication types

Case Reports

Grants and funding

This study was supported by the Innovative Research Team of High-Level Local Universities in Shanghai (SHSMU-ZDCX20211002).