Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland

Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0092523. doi: 10.1128/aac.00925-23. Epub 2024 Jan 3.


We describe the inter-regional spread of a novel ESBL-producing Escherichia coli subclone (ST131H89) in long-term care facility residents, general population, and environmental water sources in Western Switzerland between 2017 and 2020. The study highlights the importance of molecular surveillance for tracking emerging antibiotic-resistant pathogens in healthcare and community settings.

Keywords: Escherichia coli; ST131; antimicrobial resistance; long-term care facility; molecular epidemiology; surveillance.

MeSH terms

  • Anti-Bacterial Agents
  • Escherichia coli / genetics
  • Escherichia coli Infections* / epidemiology
  • Escherichia coli Proteins* / genetics
  • Humans
  • Molecular Epidemiology
  • Switzerland
  • beta-Lactamases


  • Escherichia coli Proteins
  • Anti-Bacterial Agents
  • beta-Lactamases