Intraluminal bile salt increases rate of firing in afferent fibers from the small intestine of the rat

Experientia. 1987 Feb 15;43(2):168-9. doi: 10.1007/BF01942837.

Abstract

Perfusion of a rat intestinal segment with a solution containing sodium deoxycholate (8 mM) increases the rate of firing in periarterial afferent nerves from the gut. This observation indirectly supports our earlier proposal that bile salt evokes a net fluid secretion in the small intestine via an activation of the enteric nervous system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Afferent Pathways / drug effects
  • Afferent Pathways / physiology*
  • Animals
  • Deoxycholic Acid / pharmacology*
  • In Vitro Techniques
  • Intestine, Small / innervation*
  • Male
  • Perfusion
  • Rats
  • Rats, Inbred Strains

Substances

  • Deoxycholic Acid