Mnemonic effects of asthma medication in children

J Asthma. 1986;23(6):291-6. doi: 10.3109/02770908609073175.


Asthmatic children receiving theophylline or steroid-theophylline combination therapy and normal nonasthmatics were given tests of visual retention and paired-associate learning. The performance of children receiving combination therapy was significantly worse than that of the nonasthmatics 6-8 hours after receiving steroid medication, but not 22-24 or 46-48 hours after medication. Children receiving theophylline alone did not differ from nonasthmatics on these tasks. These observations suggest that steroid-inclusive medication regiments can affect cognitive performance.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Asthma / drug therapy*
  • Asthma / psychology
  • Child
  • Drug Therapy, Combination
  • Humans
  • Memory / drug effects*
  • Steroids / adverse effects*
  • Steroids / therapeutic use
  • Theophylline / adverse effects*
  • Theophylline / therapeutic use
  • Time Factors


  • Steroids
  • Theophylline