Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 40 (2), 185-9

Diffuse Axonal Injury in Early Infancy

Diffuse Axonal Injury in Early Infancy

G H Vowles et al. J Clin Pathol.


Diffuse axonal injury typified by retraction balls and axonal swellings was identified in the brains of a series of infants, 5 months old and younger, who had suffered closed head injuries. These axonal discontinuities were shown by using Nauomenko and Feigin's silver method, which is particularly useful for showing fine axons such as those found in the developing brain. Diffuse axonal injury in early infancy may occur in the same way as that described in adults. The low incidence of intracerebral haematomata suggests that recurrent trauma to the head from a combination of direct contact and shaking results in axonal damage to the poorly myelinated axons and that blood vessels are rarely damaged.

Similar articles

See all similar articles

Cited by 8 articles

See all "Cited by" articles


    1. J Neurol Neurosurg Psychiatry. 1956 Aug;19(3):163-85 - PubMed
    1. Stain Technol. 1979 Jul;54(4):193-200 - PubMed
    1. Pediatrics. 1967 Oct;40(4):596-602 - PubMed
    1. J Clin Pathol. 1984 Oct;37(10):1095-1100 - PubMed
    1. Arch Pathol Lab Med. 1986 Jun;110(6):485-8 - PubMed

LinkOut - more resources