Accelerated myelination in early Sturge-Weber syndrome demonstrated by MR imaging

J Comput Assist Tomogr. 1987 Mar-Apr;11(2):226-31. doi: 10.1097/00004728-198703000-00005.


Magnetic resonance imaging of the brain in two infants with Sturge-Weber syndrome has demonstrated a pattern of accelerated myelination in the abnormal cerebral hemisphere. The extent of myelination was most apparent on the T1-weighted inversion recovery sequence while the T2-weighted images demonstrated concomitant changes in hydration of the brain. We propose an explanation for this finding based on cerebral ischemia underlying the leptomeningeal angioma.

Publication types

  • Case Reports

MeSH terms

  • Angiomatosis / pathology*
  • Brain / pathology*
  • Choroid Plexus / pathology
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Spectroscopy*
  • Myelin Sheath / pathology*
  • Sturge-Weber Syndrome / pathology*
  • Time Factors