Dr Erik von Willebrand first described a family with bleeding symptoms in a Finnish publication in 1926. A closer look at this landmark publication sheds light on some pathophysiological aspects of von Willebrand disease that may be applicable even in the current era. We attempt to relay in this article how the teachings from this original description may provide a benchmark for further research in this condition.
Keywords: bleeding; estrogen; history; von Willebrand disease.
© 2023 The Authors.