Adverse reactions to xenon-enhanced CT cerebral blood flow determination

Radiology. 1987 Apr;163(1):251-4. doi: 10.1148/radiology.163.1.3823444.


Fourteen institutions performed 1,830 computed tomographic (CT) cerebral blood flow (CBF) examinations with 32% inhaled stable xenon. Respiratory rate delay greater than 10 seconds occurred in 3.6% of patients, with 83% of the delays lasting 10-15 seconds. There was no incident of prolonged respiratory difficulty. Headache (0.4%), seizures (0.2%), nausea and vomiting (0.2%), and change in neurologic status (0.1%) were uncommon, and there were no transient ischemic attacks. The CT CBF method with 32% inhaled stable xenon is thus associated with an acceptably low incidence of adverse reactions.

MeSH terms

  • Brain / blood supply
  • Cerebrovascular Circulation*
  • Depression, Chemical
  • Headache / chemically induced
  • Humans
  • Nausea / chemically induced
  • Respiration / drug effects
  • Seizures / chemically induced
  • Tomography, X-Ray Computed*
  • Vomiting / chemically induced
  • Xenon / adverse effects*


  • Xenon