Bilateral peripheral ulcerative keratitis in a patient with known Sézary syndrome

Am J Ophthalmol Case Rep. 2023 Dec 24:33:101990. doi: 10.1016/j.ajoc.2023.101990. eCollection 2024 Mar.

Abstract

Purpose: To report a case of bilateral peripheral ulcerative keratitis (PUK) in a patient with underlying Sézary syndrome.

Observations: A 58-year-old male presented with bilateral corneal ulceration with stromal thinning and was diagnosed with PUK. He was actively being treated for Sézary syndrome, a cutaneous T-cell lymphoma. He had no lagophthalmos or other adnexal abnormalities that would lead to ocular surface breakdown. A systemic autoimmune and infectious workup for PUK was unremarkable. His keratitis resolved after treatment with oral prednisone.

Conclusions and importance: We describe a previously undocumented association of PUK with Sézary syndrome in a patient without adnexal disease.

Keywords: Mycosis fungoides; Peripheral ulcerative keratitis; Sézary syndrome.

Publication types

  • Case Reports