Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease

Curr Gastroenterol Rep. 2024 Feb;26(2):31-40. doi: 10.1007/s11894-024-00915-x. Epub 2024 Jan 20.


Purpose of review: Intestinal ultrasound (IUS) is a non-invasive, accurate, and well-tolerated tool that provides real-time assessment of inflammatory bowel disease (IBD) activity and is therefore an ideal monitoring tool. This review describes the evolving role of IUS in each phase of clinical management of IBD.

Recent findings: Accumulating evidence has demonstrated that IUS is an excellent tool for the assessment of suspected IBD, with a very high negative predictive value. It accurately assesses disease activity, disease complications, and in the pre-treatment phase, provides a benchmark for subsequent follow-up. IUS can detect early therapeutic response and correlates well with other established monitoring modalities with arguably superior predictive capabilities and ability to assess a deeper degree of remission, transmural healing (TH). IUS has a crucial role in the management of IBD and has ushered in a new era of monitoring with more rapid evaluation and the opportunity for early optimization, deeper therapeutic targets, and improved outcomes.

Keywords: Clinical application; Crohn’s disease; Disease monitoring; Inflammatory bowel disease; Intestinal ultrasound; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Humans
  • Inflammatory Bowel Diseases* / complications
  • Inflammatory Bowel Diseases* / diagnostic imaging
  • Inflammatory Bowel Diseases* / therapy
  • Intestines / diagnostic imaging
  • Ultrasonography