Abstract
A trial was carried out to assess the efficacy of a nitrophenylguanidine compound, netobimin against Dicrocoelium dendriticum in naturally infected sheep. At a dose rate of 20 mg/kg bodyweight administered orally the drug was highly effective, producing a mean reduction of 98.9 per cent in the fluke burdens of treated animals compared with untreated controls. No side effects were observed in the treated sheep.
MeSH terms
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Animals
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Anthelmintics / therapeutic use*
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Dicrocoeliasis / drug therapy
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Dicrocoeliasis / veterinary*
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Dicrocoelium / drug effects
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Gallbladder / parasitology
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Guanidines / therapeutic use*
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Intestine, Small / parasitology
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Liver / parasitology
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Liver Diseases, Parasitic / drug therapy
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Liver Diseases, Parasitic / veterinary*
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Parasite Egg Count
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Sheep
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Sheep Diseases / drug therapy*
Substances
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Anthelmintics
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Guanidines
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netobimin