An evaluation of the efficacy of netobimin against Dicrocoelium dendriticum in sheep

Vet Rec. 1987 Jan 17;120(3):57-8. doi: 10.1136/vr.120.3.57.

Abstract

A trial was carried out to assess the efficacy of a nitrophenylguanidine compound, netobimin against Dicrocoelium dendriticum in naturally infected sheep. At a dose rate of 20 mg/kg bodyweight administered orally the drug was highly effective, producing a mean reduction of 98.9 per cent in the fluke burdens of treated animals compared with untreated controls. No side effects were observed in the treated sheep.

MeSH terms

  • Animals
  • Anthelmintics / therapeutic use*
  • Dicrocoeliasis / drug therapy
  • Dicrocoeliasis / veterinary*
  • Dicrocoelium / drug effects
  • Gallbladder / parasitology
  • Guanidines / therapeutic use*
  • Intestine, Small / parasitology
  • Liver / parasitology
  • Liver Diseases, Parasitic / drug therapy
  • Liver Diseases, Parasitic / veterinary*
  • Parasite Egg Count
  • Sheep
  • Sheep Diseases / drug therapy*

Substances

  • Anthelmintics
  • Guanidines
  • netobimin