African countries from the Pasteur Network reexamine their syndromic sentinel surveillance system associated with household contact within the AFROSCREEN program

Front Public Health. 2024 Jan 5:11:1292435. doi: 10.3389/fpubh.2023.1292435. eCollection 2023.

Abstract

Surveillance to better detect and respond to new pathogens remains a major challenge for global public health. The Pasteur Network recently held a brainstorming workshop located in Cameroon attended by Pasteur epidemiological teams from Niger, Central African Republic (CAR), Cameroon, Senegal, and Madagascar to discuss how the Pasteur Network in Africa could use the lessons of COVID-19 to set-up a pilot sentinel surveillance scheme given its expertise and involvement during the pandemic. The possibility of coupling sentinel syndromic and biological surveillance already implemented for influenza surveillance with the recent sequencing capacity put in place by the AFROSCREEN program prompted us to consider strengthening surveillance tools to target "Pathogen X" detection in Africa. The perspective project provided by the Pasteur Network teams and shared with other partners of the AFROSCREEN program will target strengthening of the diagnosis of severe acute respiratory infections (IRAS) and the surveillance of IRAS, the evaluation of the impact of SARS-CoV-2 on the epidemiology of IRAS, and the addition of the detection of new pathogens, called "Pathogen X," based on sequencing capacity and epidemiological criteria from One Health approaches.

Keywords: epidemiology; preparedness; sentinel surveillance system; sequencing; syndromic surveillance; “pathogen X”.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa
  • African People
  • Black People
  • COVID-19 / epidemiology
  • Cameroon / epidemiology
  • Central African Republic / epidemiology
  • Humans
  • Madagascar / epidemiology
  • Niger / epidemiology
  • Respiratory Tract Infections* / diagnosis
  • Respiratory Tract Infections* / epidemiology
  • Respiratory Tract Infections* / etiology
  • Senegal / epidemiology
  • Sentinel Surveillance*

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Agence Française de Développement through the AFROSCREEN project (grant agreement CZZ3209), coordinated by the ANRS|Maladies infectieuses émergentes in partnership with Institut Pasteur and IRD.