Treatments and regulatory mechanisms of acoustic stimuli on mood disorders and neurological diseases

Yikai Chen; Julianne Sun; Junxian Tao; Tao Sun

doi:10.3389/fnins.2023.1322486

Treatments and regulatory mechanisms of acoustic stimuli on mood disorders and neurological diseases

Front Neurosci. 2024 Jan 5:17:1322486. doi: 10.3389/fnins.2023.1322486. eCollection 2023.

Authors

Yikai Chen¹, Julianne Sun², Junxian Tao¹, Tao Sun¹

Affiliations

¹ Center for Precision Medicine, School of Medicine and School of Biomedical Sciences, Huaqiao University, Xiamen, China.
² Xiamen Institute of Technology Attached School, Xiamen, China.

Abstract

Acoustic stimuli such as music or ambient noise can significantly affect physiological and psychological health in humans. We here summarize positive effects of music therapy in premature infant distress regulation, performance enhancement, sleep quality control, and treatment of mental disorders. Specifically, music therapy exhibits promising effects on treatment of neurological disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD). We also highlight regulatory mechanisms by which auditory intervention affects an organism, encompassing modulation of immune responses, gene expression, neurotransmitter regulation and neural circuitry. As a safe, cost-effective and non-invasive intervention, music therapy offers substantial potential in treating a variety of neurological conditions.

Keywords: acoustic stimuli; brain development; mood disorder; music therapy; neurological diseases; noise exposure.

Publication types

Review

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Scientific Research Funds of Huaqiao University (Z16Y0017, TS), and the National Natural Science Foundation of China (32271002, TS).