The authors studied a total of 218 patients with such pathological states as neuroses with vegetovascular crises, the hypothalamic syndrome, temporal epilepsy, and neurogenic syncopes (four groups). Clinical peculiarities of psychovegetative manifestations and the status of autonomic regulation were analyzed in the above groups. The authors consider the role of a number of factors exercising influence on the organization of the functional regulation of the autonomic nervous system, the degree of changes in the psychological sphere, the nature of the pathological process, the level of damage to the cerebral structures, and the status of the initial vegetative tonus. It has been established that each of the above factors has different significance with regard to the formation of the adaptive behaviour of patients.