NBD-based colorimetric and ratiometric fluorescent probe in NIR for bisulfite

Feng Li; Shu-Mei Zhai; Jun-Jie Xian-Yu; Bao-Xiang Zhao; Zhao-Min Lin

doi:10.1016/j.talanta.2024.125684

NBD-based colorimetric and ratiometric fluorescent probe in NIR for bisulfite

Talanta. 2024 May 1:271:125684. doi: 10.1016/j.talanta.2024.125684. Epub 2024 Jan 17.

Authors

Feng Li¹, Shu-Mei Zhai¹, Jun-Jie Xian-Yu², Bao-Xiang Zhao³, Zhao-Min Lin⁴

Affiliations

¹ School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, PR China.
² Institute of Medical Sciences, The Second Hospital of Shandong University, Jinan, 250033, PR China.
³ School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, PR China. Electronic address: bxzhao@sdu.edu.cn.
⁴ Institute of Medical Sciences, The Second Hospital of Shandong University, Jinan, 250033, PR China. Electronic address: linzhaomin@sdu.edu.cn.

PMID: 38262131
DOI: 10.1016/j.talanta.2024.125684

Abstract

This work presented a FRET-ICT based fluorescent probe (named NTC) composed of coumarin-benzothiazole as the acceptor and 4-nitrobenzo[c][1,2,5] oxadiazole (NBD) as the donor for the detection of SO₂ derivatives in NIR. Probe NTC possessed superior performance including selectivity, quickly response toward SO₃^2-/HSO₃^- and high energy transfer efficiency (94 %). The test strips provided a simple and effective tool in detecting the presence of bisulfite. Besides, NTC was applied to test the sulfur dioxide derivatives in food samples and cells.

Keywords: Bisulfite; Cell imaging; FRET; Fluorescent probe; Food samples; Test strips.

MeSH terms

Colorimetry*
Fluorescence Resonance Energy Transfer
Fluorescent Dyes*
HeLa Cells
Humans
Sulfites
Sulfur Dioxide

Substances

Fluorescent Dyes
hydrogen sulfite
Sulfur Dioxide
Sulfites