A randomized, controlled pilot study of oral roflumilast compared with intramuscular methotrexate for plaque and scalp psoriasis

J Am Acad Dermatol. 2024 May;90(5):1063-1065. doi: 10.1016/j.jaad.2024.01.018. Epub 2024 Jan 22.

Authors

Dina G Saadi¹, Mohamed H M El-Komy¹, Hadeer Khedr¹, Nevine Shawky¹, Amira Aly Hegazy², Yousra Azzazi³, Aya M AlOrbani¹

Affiliations

¹ Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
² Public Health and Community Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
³ Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt. Electronic address: yosrazzazi@cu.edu.eg.

PMID: 38266682
DOI: 10.1016/j.jaad.2024.01.018

No abstract available

Keywords: phosphodiesterase 4; psoriasis; roflumilast; scalp psoriasis.

Publication types

Randomized Controlled Trial

MeSH terms

Aminopyridines*
Benzamides*
Cyclopropanes
Double-Blind Method
Humans
Methotrexate* / therapeutic use
Pilot Projects
Psoriasis* / drug therapy
Scalp
Severity of Illness Index
Treatment Outcome

Substances

Methotrexate
Roflumilast
Aminopyridines
Benzamides
Cyclopropanes