Neurocysticercosis: A neglected but preventable cause of seizure in adults

Clin Case Rep. 2024 Jan 23;12(1):e8454. doi: 10.1002/ccr3.8454. eCollection 2024 Jan.

Abstract

Neurocysticercosis is an infection of the central nervous system caused by the larval stage of Taenia solium. Although endemic in sub-Saharan Africa, it is neglected but remains a significant cause of preventable seizure in adults. Its diagnosis is challenging and is frequently missed due to its variable clinical manifestations and lack of diagnostic facilities in most areas of sub-Saharan Africa. This report discusses two cases of parenchymal neurocysticercosis in Ghanaians who presented to the emergency unit of a District Hospital with adult-onset seizures. The two cases highlight the need for a high index of suspicion and also underscore the important role of neuroimaging in the evaluation of patients presenting with adult-onset seizures in neurocysticercosis endemic areas. This is necessary for prompt detection and initiation of appropriate therapy in order to improve prognosis.

Keywords: Cysticercosis; Neurocysticercosis; Taenia solium; epilepsy; focal seizure; neuroimaging.

Publication types

  • Case Reports