Leptomeningeal tumor spread or immune checkpoint inhibitor-related encephalitis/(poli-)neuritis? An unsolved dilemma in a patient on pembrolizumab for a history of brain metastases from lung adenocarcinoma

Acta Neurol Belg. 2026 Feb;126(1):385-386. doi: 10.1007/s13760-023-02462-0. Epub 2024 Jan 25.

¹ Radiation Oncology Unit, REM Radioterapia Srl, 95029, Viagrande, Italy. gianluca.ferini@grupposamed.com.
² Radiation Oncology Unit, REM Radioterapia Srl, 95029, Viagrande, Italy.
³ Radiology Unit, Giovanni Paolo II Hospital, 97100, Ragusa, Italy.
⁴ Medical Oncology, University Hospital Policlinico San Marco, 95123, Catania, Italy.
⁵ Department of Biomedical, Dental and Morphological and Functional Imaging Sciences, University of Messina, 98122, Messina, Italy.

No abstract available

Keywords: Adverse effects; Brain metastasis; Diplopia; Encephalitis; Immunotherapy; Lung cancer; Pembrolizumab; Radiotherapy; Tinnitus.