Incidental Prostate-Specific Membrane Antigen-Avid Vestibular Schwannoma Detected on 68 Ga-Prostate-Specific Membrane Antigen PET/CT

Clin Nucl Med. 2024 Mar 1;49(3):234-236. doi: 10.1097/RLU.0000000000005028. Epub 2024 Jan 25.

Abstract

A 62-year-old man was referred for a 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for newly diagnosed prostate cancer (ISUP grade 5), on the background of left vestibular schwannoma treated with surgical excision 25 years ago. PSMA PET study confirmed the presence of PSMA-avid malignancy in the left prostate lobe with no evidence of PSMA-avid nodal or distant metastasis. An incidental PSMA-avid focus (SUV max , 4.3) was identified in the region of the left cerebellopontine angle, which corresponded to a homogeneous enhancing lesion centered at the left internal acoustic canal and left cerebellopontine angle on MRI. The combined PSMA PET findings and MRI characteristics were consistent with recurrent vestibular schwannoma.

Publication types

  • Case Reports

MeSH terms

  • Edetic Acid
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Male
  • Middle Aged
  • Neuroma, Acoustic* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Prostate / pathology
  • Prostate-Specific Antigen
  • Prostatic Neoplasms* / pathology

Substances

  • Gallium Isotopes
  • Gallium-68
  • Gallium Radioisotopes
  • Prostate-Specific Antigen
  • Edetic Acid