Theory of mind in neurodevelopmental disorders: beyond autistic spectrum disorder

Abstract

Introduction: Theory of mind (ToM) is the human ability to perceive, interpret, and attribute the mental states of other people, and the alteration of this cognitive function is a core symptom of autistic spectrum disorder (ASD). In such other neurodevelopmental disorders as childhood-onset obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) that can present with cognitive dysfunctions, ToM has been less extensively studied, especially in the young population. The aim of the study was to compare advanced ToM between groups of young people diagnosed with OCD, TS, or ASD and a control group.

Methods: Clinical interviews were conducted with male patients aged between 11 and 17 years with a main diagnosis of OCD (n = 19), TS (n = 14), or ASD (n = 18), and a control group (n = 20). We administered instruments for estimating intelligence quotient and severity of psychiatric symptoms, and tasks to evaluate ToM (the "Stories from everyday life" task and the "Reading the mind in the eyes" test).

Results: Young people with TS and with ASD present similar difficulties in solving advanced ToM tasks, whereas patients with childhood-onset OCD present similar results to controls.

Conclusions: ToM is altered in other neurodevelopmental disorders beyond ASD, such as TS.

Keywords: Autistic spectrum disorder; Cognición social; Neurodevelopmental disorders; Obsessive-compulsive disorder; Social cognition; Síndrome de tourette; Teoría de la mente; Theory of mind; Tourette syndrome; Trastorno del espectro autista; Trastorno obsesivo-compulsivo; Trastornos del neurodesarrollo.