Tuberculosis and kidney transplantation

Acta Med Scand. 1979;205(7):637-40. doi: 10.1111/j.0954-6820.1979.tb06118.x.

Abstract

Immunosuppressive treatment enhances the risk of pulmonary and other infections. Tuberculosis is a predictable complication in transplanted patients. The present material comprises 584 kidney transplantation patients, ten of whom had had a previous history of tuberculosis. After transplantation ten patients presented with pulmonary tuberculosis during immunosuppressive treatment. One of the patients to whom no prophylactic antituberculous treatment had been given presented with a relapsing tuberculosis. The results of routine antituberculous treatment were excellent, but graft and patient survival were disappointing among the tuberculosis patients.

MeSH terms

  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use
  • Azathioprine / adverse effects
  • Female
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Kidney Transplantation*
  • Male
  • Methylprednisolone / adverse effects
  • Middle Aged
  • Postoperative Complications / prevention & control*
  • Transplantation, Homologous
  • Tuberculosis, Pulmonary / etiology*

Substances

  • Antitubercular Agents
  • Immunosuppressive Agents
  • Azathioprine
  • Methylprednisolone