Coccidioidomycosis presenting years after returning from travel

Koos Korsten; Josje Altenburg; Marieke Gittelbauer; Peter van Hengel; Rogier Jansen; Karin van Dijk

doi:10.1016/j.mmcr.2023.100623

Coccidioidomycosis presenting years after returning from travel

Med Mycol Case Rep. 2023 Dec 30:43:100623. doi: 10.1016/j.mmcr.2023.100623. eCollection 2024 Mar.

Authors

Koos Korsten¹, Josje Altenburg², Marieke Gittelbauer¹, Peter van Hengel³, Rogier Jansen⁴, Karin van Dijk¹

Affiliations

¹ Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Amsterdam Medisch Centrum, Meibergdreef 9, Amsterdam, the Netherlands.
² Department of Respiratory Medicine, Amsterdam UMC, Amsterdam Medisch Centrum, Meibergdreef 9, Amsterdam, the Netherlands.
³ Department of Pulmonary Diseases, Flevo Hospital, Almere, the Netherlands.
⁴ Department of Medical Microbiology, OLVG, Amsterdam, the Netherlands.

Abstract

After having traveled to California in 2017, a 26-year old Dutch man presented in 2020 with persisting cough and shortness of breath. Radiology showed cystic bronchiectasis with peri-bronchial consolidation in his right upper lobe. Laboratory studies in August 2021 showed an increased total IgE, specific Aspergillus IgE, eosinophilia and positive BAL culture for Coccidioides immitis/posadasii. After 6 weeks of itraconazole treatment for suspected allergic bronchopulmonary aspergillosis, symptoms persisted and respiratory cultures remained positive. The infection was cleared after a 6-month course of fluconazole. (max 75 words).

Keywords: Coccidioidomycosis; Microbiology; Mycology; Pulmonary.

Publication types

Case Reports