Cerebral Embolism and MINOCA Secondary to Left Atrial Myxoma after Occlusion of Atrial Septal Defect by Amplatzer Occluder: A Case Report

Heart Surg Forum. 2024 Jan 9;27(1):E006-E013. doi: 10.59958/hsf.5803.


Primary heart tumors are rare, with atrial myxomas being the most common type. Atrial myxomas can lead to embolisms, heart obstruction, and systemic symptoms. Herein, we report a case of 72-year-old woman who presented with a left atrial myxoma at the atrial septal defect occluder, a new acute cerebral infarction, and MINOCA (myocardial infarction with no obstructive coronary atherosclerosis). Left atrial myxoma is a common primary cardiac tumor; however, left atrial myxomas arising after percutaneous atrial septal defect occlusion are rare. Additionally, the patient presented with a new case of multiple systemic emboli. The patient underwent surgical resection of a left atrial myxoma, occluder, and left atrium, and atrial septal repair, and was discharged with good recovery for outpatient follow-up. The possibility of a cardiac tumor, especially an atrial myxoma, which can lead to a series of complications, should be considered at the closure site after percutaneous atrial septal closure. Therefore, active surgical treatment and long-term follow-up are warranted in such cases.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Catheterization / adverse effects
  • Embolism* / diagnosis
  • Embolism* / etiology
  • Embolism* / surgery
  • Female
  • Heart Atria / surgery
  • Heart Neoplasms* / complications
  • Heart Neoplasms* / diagnosis
  • Heart Neoplasms* / surgery
  • Heart Septal Defects, Atrial* / complications
  • Heart Septal Defects, Atrial* / diagnosis
  • Heart Septal Defects, Atrial* / surgery
  • Humans
  • Intracranial Embolism* / diagnosis
  • Intracranial Embolism* / etiology
  • Intracranial Embolism* / surgery
  • Myxoma* / complications
  • Myxoma* / diagnosis
  • Myxoma* / surgery
  • Septal Occluder Device* / adverse effects