Abstract
A family was recently studied in which two brothers with identical HLA serotypes had allergic bronchopulmonary aspergillosis. One of the two had a normal bronchogram. A field investigation of the family residence showed that a barn was the probable source of the organism causing disease in these patients. Immunologic characterization of the family members showed a broad spectrum of response to the environmental exposure.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Adult
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Aspergillosis, Allergic Bronchopulmonary / diagnostic imaging
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Aspergillosis, Allergic Bronchopulmonary / genetics*
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Aspergillosis, Allergic Bronchopulmonary / immunology
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Asthma / complications
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Bronchography
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Child
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Child, Preschool
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Conjunctivitis / complications
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Disease Reservoirs
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Female
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HLA Antigens / analysis
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Humans
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Immunologic Techniques
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Infant
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Infant, Newborn
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Male
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Middle Aged
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Rhinitis / complications
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Skin Tests