Computer program for calculation of kinetic and pharmacologic parameters using a 'direct linear plot' derived algorithm

Comput Methods Programs Biomed. 1987 Feb;24(1):41-5. doi: 10.1016/0169-2607(87)90064-2.

Abstract

Data processing using nonparametric statistics was performed using a 'direct linear plot' algorithm of ECB. ECB (Eisenthal and Cornish-Bowden) is a computer program designed to calculate the Km and V parameters in enzyme kinetics. It is also suitable for estimation of EC50 (ligand or drug concentration for 50% effect) in pharmacological studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Enzymes / metabolism*
  • Kinetics
  • Mathematical Computing*
  • Pharmacology*
  • Software*

Substances

  • Enzymes