Aldosterone Synthase Inhibitors and Mineralocorticoid Receptor Antagonists: Competitors or Collaborators?

Circulation. 2024 Feb 6;149(6):414-416. doi: 10.1161/CIRCULATIONAHA.123.066314. Epub 2024 Feb 5.

Authors

Bertram Pitt¹, Gordon H Williams²

Affiliations

¹ Department of Medicine, School of Medicine, University of Michigan, Ann Arbor (B.P.).
² Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (G.H.W.).

PMID: 38315762
DOI: 10.1161/CIRCULATIONAHA.123.066314

No abstract available

Keywords: aldosterone; cytochrome P-450 CYP11B2; hypertension; receptors, mineralocorticoid.

MeSH terms

Aldosterone*
Cytochrome P-450 CYP11B2
Humans
Hypertension*
Mineralocorticoid Receptor Antagonists / adverse effects
Receptors, Mineralocorticoid
Spironolactone

Substances

Aldosterone
Mineralocorticoid Receptor Antagonists
Cytochrome P-450 CYP11B2
Spironolactone
Receptors, Mineralocorticoid