Differences in hidradenitis suppurativa patterns of cutaneous involvement between sexes: Insights from a cross-sectional study

Hum Immunol. 2024 Mar;85(2):110764. doi: 10.1016/j.humimm.2024.110764. Epub 2024 Feb 6.

Abstract

Hidradenitis suppurativa is a chronic, inflammatory condition of the pilosebaceous unit in which patients manifest multiple, painful cutaneous nodules, abscesses and tunnels. These lesions are described to affect the intertriginous zones, however, the condition exhibits significant phenotypic variability. Such variability is influenced by the patients lifestyle, genetic predisposition and sex. In this cross-sectional study, we investigate sex differences in patterns of hidradenitis suppurativa skin involvement, specifically at site of first involvement and most bothersome cutaneous site of involvement.

Keywords: Hidradenitis Suppurativa; Phenotype; Sex.

MeSH terms

  • Cross-Sectional Studies
  • Female
  • Genetic Predisposition to Disease
  • Hidradenitis Suppurativa* / epidemiology
  • Hidradenitis Suppurativa* / pathology
  • Humans
  • Male