Hip and pelvis region MRI reference image atlas for scoring inflammation in peripheral joints and entheses according to the OMERACT-MRI WIPE scoring system in patients with spondyloarthritis

Mikkel Østergaard; Robert Gw Lambert; Anna Ef Hadsbjerg; Iris Eshed; Walter P Maksymowych; Ashish J Mathew; Lennart Jans; Susanne J Pedersen; Philippe Carron; Yasser Emad; Gabriele De Marco; Paul Bird; Maria S Stoenoiu; Violaine Foltz; Joel Paschke; Helena Marzo-Ortega; Signe Møller-Bisgaard; Philip G Conaghan; Marie Wetterslev

doi:10.1016/j.semarthrit.2024.152383

Hip and pelvis region MRI reference image atlas for scoring inflammation in peripheral joints and entheses according to the OMERACT-MRI WIPE scoring system in patients with spondyloarthritis

Semin Arthritis Rheum. 2024 Apr:65:152383. doi: 10.1016/j.semarthrit.2024.152383. Epub 2024 Feb 2.

Authors

Mikkel Østergaard¹, Robert Gw Lambert², Anna Ef Hadsbjerg³, Iris Eshed⁴, Walter P Maksymowych⁵, Ashish J Mathew⁶, Lennart Jans⁷, Susanne J Pedersen⁸, Philippe Carron⁹, Yasser Emad¹⁰, Gabriele De Marco¹¹, Paul Bird¹², Maria S Stoenoiu¹³, Violaine Foltz¹⁴, Joel Paschke¹⁵, Helena Marzo-Ortega¹¹, Signe Møller-Bisgaard¹⁶, Philip G Conaghan¹¹, Marie Wetterslev⁸

Affiliations

¹ Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. Electronic address: mo@dadlnet.dk.
² Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
³ Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
⁴ Department of Diagnostic Imaging, Sheba Medical Center, Affiliated to the School of Medicine, Tel-Aviv University, Israel.
⁵ Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; CARE Arthritis, Edmonton, Alberta, Canada.
⁶ Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Immunology & Rheumatology, Christian Medical College, Vellore, India.
⁷ Department of Radiology, Ghent University Hospital, Ghent, Belgium.
⁸ Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark.
⁹ Department of Rheumatology, Ghent University Hospital, Ghent, Belgium; VIB Inflammation Research Centre, Ghent University, Ghent, Belgium.
¹⁰ Department of Rheumatology, Faculty of Medicine, Cairo University, Egypt.
¹¹ Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
¹² Division of Medicine, University of New South Wales, Sydney, Australia.
¹³ Department of Rheumatology, Cliniques Universitaires Saint-Luc, Institut de Recherche Experimentale et Clinique, Université Catholique de Louvain, Bruxelles, Belgium.
¹⁴ Department of Rheumatology, Sorbonne University, APHP, Pitié-Salpètrière Hospital, Paris, France.
¹⁵ CARE Arthritis, Edmonton, Alberta, Canada.
¹⁶ Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Rheumatology, Slagelse Hospital, Slagelse, Denmark.

PMID: 38325055
DOI: 10.1016/j.semarthrit.2024.152383

Abstract

Objective: To develop a reference image atlas for scoring the hip/pelvis region according to the OMERACT whole-body MRI scoring system for inflammation in peripheral joints and entheses (MRI-WIPE).

Methods: We collected image examples of each pathology, location and grade, discussed them at web-based, interactive meetings and, finally, selected reference images by consensus.

Results: Reference images for each grade and location of osteitis, synovitis and soft tissue inflammation are provided, as are definitions, reader rules and recommended MRI-sequences.

Conclusion: A reference image atlas was created to guide scoring whole-body MRIs for arthritis and enthesitis in the hip/pelvis region in spondyloarthritis/psoriatic arthritis clinical trials and cohorts.

Keywords: Enthesitis; Hip; MRI-WIPE; OMERACT; Pelvis; Psoriatic arthritis; Spondyloarthritis; Whole-body MRI.

MeSH terms

Humans
Inflammation / diagnostic imaging
Magnetic Resonance Imaging / methods
Pelvis / diagnostic imaging
Reproducibility of Results
Spondylarthritis* / diagnostic imaging
Synovitis* / diagnostic imaging